Article Side

Online Article Directory!

Hello Guest! Login or Register to submit articles!

Hair Loss and Stem Cell Research

By Naomi Mannino Subscribe to RSS | April 25th 2012 | Views:
loading
 
  



Stem Cell Research Is Promising As a Hair Loss Treatment

With stem cell research, researchers study cellular regeneration therapy using a patient's own platelet-rich plasma on the basis of wound-healing principals to treat hair loss.

Those with alopecia areata are first to see success

"We are about 40 patients into the study, but one of our patients was so thrilled that his hair started growing in after about 2 months that he alerted the local media -- and then we had to tell our story!" says Dr. John Satino, clinic director for The Hair and Scalp Clinics in Clearwater, Fla. Satino and partner and medical director Dr. Michael Markou, a primary investigator for the Merck Pharmaceutical clinical research on Propecia, have run and administered some interesting tests and documented success with alopecia areata patients in regrowing hair in a patient's bald patches. Currently they are taking on test patients and beginning to document and test the long-term effects of this treatment to test its viability as a long-term solution for hair loss. "The advantage is that we are seeing hair growth in bald areas. The disadvantage so far is that if a pattern of baldness exists down the road, the new growth can be affected by that. So far we are seeing the greatest benefit in young people suffering from alopecia areata."

How the stem cell study procedure works

The term "stem cells" is used loosely. According to the National Institutes of Health Web site information on stem cell research, an adult stem cell is a type of cell found in many organs that can transform itself into a specialized tissue or organ cell when necessary. The primary role of adult stem cells in a living organism is to maintain and repair the tissue in which they are found. Scientists have found adult stem cells in many more tissues than they once thought possible, and that has led researchers and clinicians to ask whether adult stem cells could be used for transplants like the adult blood-forming stem cells from bone marrow that have been used in transplants for 40 years. Scientists now have evidence that stem cells exist in the brain and the heart. If the differentiation of adult stem cells can be controlled in the laboratory, these cells may become the basis of transplantation-based therapies. But the isolation and identification of these stem cells throughout the human body is still in its infancy.

What this study procedure is using is actually platelet-rich plasma (PRP) isolated from the patient's own blood, explains Satino, not only the clinic director but also a biomedical engineer who has demonstrated and performed many studies, including those of Propecia and Rogaine. "The idea of this way of stimulating follicle regeneration is based on the principals of wound healing ... a sort of cellular regeneration therapy." Satino explains that when an area like the scalp is disturbed slightly, such as by abrading it gently with a laser, it shocks the body into healing mode, and when combined with the person's own growth factors in PRP drawn from his or her own blood, it can stimulate the faulty follicles into an anagen phase of growth and give them the support they need to grow. "First we draw patient's blood to separate out the small amount of PRP which contains platelet-derived growth factors, including three proteins that act in cell adhesion. These three -- called fibrin, fibronectin and vitronectin – create a matrix for cells to build upon, while the growth factors signal the epidermis and the follicle to interact with the dermal sheath. We then irritate the scalp with a laser, which moves the follicle toward an anagen phase as it tries to heal, and we inject the growth factors in the PRP, which migrate into the follicles to start the whole process. This promotes angiogenesis and mitogenesis ... a sort of jump start for the follicles. We know that adult stem cells only are useful wherever there is an injury and that they are not specialized. We are also testing the topical application of the person's PRP in addition to the effects of low-light laser therapy, Rogaine and Propecia in conjunction with this new treatment to find the most effective treatment protocols."

The outlook of stem cell research as a hair loss treatment

So far, hair in all 40 patients has grown back in patients with alopecia areata. "It seems this procedure has the best results for the younger patient. The youngest we have treated is 15 so far, but the most important thing is to test the long-term results." Satino adds that they have also begun soaking hair transplants in PRP and injecting into transplant incisions and have gotten faster healing and thicker, faster hair regrowth in transplant patients. "But again," cautions Satino, "we don't know how the balding pattern may affect this procedure. For example, in a transplant patient, if the hairline recedes further, he will be required to get additional transplants to cover the new balding area. We have definitely found our new procedure to be most effective on bald patches in the crown and back of a patient's head. A patient may still need to supplement results with Minoxidil, Propecia or laser hair therapy."

Proving the result, getting FDA approval

So far, the procedure is approved by the FDA as a soft-tissue injection for wound healing in hair transplants, not for hair regrowth. "In the meantime, we are taking on new patients to test the procedure at about one-quarter the price of a typical transplant procedure," Satino states. "We are documenting all the results with a cast, and we mark the spot and count the hairs in one square centimeter. We test and measure hair strength and diameter and we do a recount in three months, six months and one year along with photos to document results." He adds, "We plan to publish results in some peer-reviewed dermatology, hair transplant and laser journals in the coming year. We have refrained from performing the double-blind placebo tests and the independent review boards until we have the funding and the basis to do so to gain FDA approval as a long-term hair loss treatment.

Feedback from the hair loss treatment community

While the local news has picked up the story and the clinic is getting test patients from all over the world, Bob Rider, owner of Hair Replacement Clinic in Dayton, Ohio, who has been in the business for more than 40 years, says he wishes it could be that simple. "Growing hair where there is none existing for any reason is like growing a new organ. It's just not at all simple." Dr. Sara Wasserbauer, a board-certified, California-based hair transplant surgeon, adds that in the hair community, "We're always looking for the clue to growing hair, and looking toward science and previous studies, as this study has, definitely holds some promise. But at this point, it's too soon to tell, because there is no consistency in the results yet."

Naomi Mannino - About Author:
Naomi Mannino is a freelance writer who writes about health, beauty, and fashion. She is a contributing writer for HairLossDotCom and writes about hair loss treatment and hair loss conditions such as alopecia areata.

Share on Facebook Tweet It Stumbleupon this post This post is delicious !

Article Source:
http://www.articleside.com/health-articles/hair-loss-and-stem-cell-research.htm

Related Health Articles Subscribe to RSS

Buy Zulvera-The best hair loss product
Published by John Abrahm on December 20th 2011 | Health
Hair is an essential feature which adds on to our personality and confidence level. Moreover good an...
 
Getting the most out of your naturally curly hair
Published by Mary Porter on June 21st 2012 | Health
If you have naturally curly hair then you want to ensure that you are getting the most out of your h...
 
What are the aspects through which hair loss treatment for women help out?
Published by Justin Mark on December 22nd 2011 | Health
It is a nightmare, for every person in this world, who watches his/her broken hair on the pillows es...
 
Go for hair loss cure with the best hair loss treatment procedures in the market
Published by Makjonson on January 12th 2012 | Health
Although the hair loss cure process is quite costly and not hundred percent effective you can still ...
 
Best Laser hair removal deals in Melbourne
Published by MAIRE Patton on July 4th 2012 | Health
Where would you find the best deal for hair removal today? One of the best ways to locate the deals ...
 
Hair loss treatment for continued hair loss
Published by Makjonson on February 15th 2012 | Health
Hair loss treatment is usually not very cost effective. There is no sure way to save you from hair l...
 
Try new hairstyle daily with awesome hair extensions
Published by Jane Cyrus on March 6th 2012 | Health
Hairs give unique appearance to every human being as they all have different cuts and styles which s...
 
Have Long and Beautiful hairs with Human hair extensions
Published by Jane Cyrus on April 18th 2012 | Health
Hairs depict the personality of the human being clearly and it is noticed by every person....
 
Stop your hair fall with the aid of diet
Published by Carsonmrtn08 on July 11th 2012 | Health
People fail to implement good eating measures as well as take proper care of their from the initial ...
 
How smoking and hair loss are related
Published by Jacques Fernadiz on April 11th 2012 | Health
Smoking and hair loss are related and by refusing to oblige with your nicotine pangs, you can possib...
 
Natural remedies for hair loss cure
Published by Makjonson on February 3rd 2012 | Health
This article is focuses on the common problem of hair loss. Hair loss cure treatment can be taken to...
 
Discover the effective impact of the hair loss treatment Zulvera
Published by John Abrahm on January 13th 2012 | Health
You should not be worried about the hair loss factor and should protect yourself from undergoing the...
 
What are some common ways to prevent hair loss for women?
Published by Justin Mark on December 22nd 2011 | Health
Hair loss is a situation which can happen to any person in this world. There is no person in this wo...
 
Clip in extensions – Easy Procedure to get long hairs
Published by Jane Cyrus on April 18th 2012 | Health
Extensions are the best way to give heavy and thick look to your hairs and it is now easily availabl...
 
Effective ways to get rid of hair loss problems
Published by Makjonson on January 12th 2012 | Health
Whether severe or minor, any kind of hair loss problem can be really harmful in terms of self confid...
 
Tips on how to restore hair safely
Published by Stefenm on June 6th 2012 | Health
Hair thinning and greying hair is proving to be a prevalent difficulty that the youth faces currentl...
 
Grow hair back if you lose some
Published by Makjonson on February 15th 2012 | Health
To grow hair back, you need to go through various treatments regarding hair loss. There are surgerie...
 
Some modern techniques of hair loss treatment
Published by Makjonson on January 19th 2012 | Health
These days, the treatment for the hair loss in the modern age has advanced quite up to a level. Now ...
 
Fenugreek- a natural beauty aid for the hair
Published by Ajay on July 6th 2012 | Health
Fenugreek is an herb that is commonly found in Mediterranean region. Fenugreek seeds are predominant...
 
Laser hair removal for smoother body skin & smarter looks
Published by Therese Laserase on January 4th 2012 | Health
Fashion conscious men always prefer a well-groomed look. They prefer not to have excess hair on thei...