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Canada Pharmacy Agrees Phenotyping COPD Study Reveals More Clues in Asthmatic Women

By Robert Anderson Subscribe to RSS | March 9th 2012 | Views:

Phenotyping patients are a standard procedure to understand diseases better. A recent study followed by our Canada pharmacy has identified more clues by studying chronic bronchitis in women than understanding common elements existing in lung functions or using only males in a population study.

The American Thoracic Society (ATS) questionnaire was used by researchers involved in the chronic obstructive pulmonary disease genetic epidemiology (COPDGene) study involving 1,061 patients suffering from chronic bronchitis. Stage 2-4 COPD was identified with 290 patients having sputum and cough over a period of three months per year. These patients had symptoms for around two years, while 771 patients did not demonstrate any. Results clearly indicated chronic bronchitis could help predict COPD exacerbations in the future.

FEV1 results are commonly used to identify signs of COPD, but findings from the recent studies clearly indicate many vital features are likely to be missed by just measuring lung capacity. Detailed radiographic permission and other clinical features are needed to come up with precise therapies based on allergic reactions demonstrated by individuals suffering from COPD.

Volunteers suffering from chronic bronchitis had 1.21 exacerbations per patient compared to 0.63 exacerbations per patient on a yearly basis in the case of patients not suffering from the disease. Also, 26.6% of the bronchitis-positive volunteer group had severe exacerbations. It was a matter of concern, according to our Canadian pharmacy, as 20% patients hospitalized for severe COPD exacerbations did not survive for even a year after hospitalization and treatment.

The ATS questionnaire used for the study emphasizes the fact patients suffering from chronic bronchitis will have chest CTs showing thicker airways commonly seen in patients suffering from COPD. Other factors like lung emphysema and gas trapping remain the same in patients with or without COPD.

Researchers conducted a second study involving 1,002 volunteers suffering from COPD. A 1-mm increase in wall thickness of the bronchial airways showed up on chest CT scans indicating a 1.84-fold increased COPD exacerbations per year accounting for lung functioning in patients. Patients with total emphysema beyond 35% demonstrated a 1.18-fold increased exacerbation rate per year for every 5% rise in emphysema.

Criterion used for establishing results included maintaining systemic corticosteroids with or without hospitalization for incidence of at least one COPD exacerbation. Researchers established specific information regarding rate of exacerbation in patients is needed. People do buy Combivent inhaler, a bronchodilator, to control symptoms like shortness of breath, wheezing, and cough commonly seen in patients suffering from COPD.

Several factors like smoking were considered in the study. Researchers conceded women smokers demonstrated more exacerbations by smoking cigarettes as compared to men indulging in the same lifestyle habit. Mortality rate is also higher in women, which is why the present study is vital in presenting other factors responsible for measuring accurate indicators of COPD.

Women smokers also had higher wall area percentage but smaller airway wall thickness, luminal area, and internal diameter as compared to males. Our Canada pharmacy is certain specific information related to exacerbations in women suffering from COPD will help specialists prescribe accurate generic Combivent bringing relief from symptoms of the disease quickly and on a more permanent basis.

Robert Anderson - About Author:
Robert Anderson is specializing in writing articles on how to save on medication by buying from canadian pharmacy. For more information about the author and savings on canadianpharmacy please visit

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